in children. although its burden is considerably preventable by vaccine, routine vaccination against hib has not been defined in the national immunization program of iran. this study was performed to assess the cost-benefit and cost‑utility of running an hib vaccination program in iran. methods: based on a previous systematic review and meta‑analysis for vaccine efficacy, we estimated the avert...

conclusions the use of sof + pr regimen or ldv/sof can significantly reduce the incidence of complications associated with the disease. for example, short and long-term outcomes are better than the current drug regimens for hcv genotype 1 patients in all stages of the disease. objectives this study is aimed to assess the cost-effectiveness of the three drug regimens of pegylated interferon and ...

background: galactosemia is a congenital metabolic disorder that can damage the health of a newborn. screening is an important step to prevent and treat this condition. due to increasing health care costs and limited financial resources of health systems, the most suitable economic analysis tool should be applied. the aim of this study was to analyze the cost-utility of neonatal screening progr...

background: helicobacter pylori may cause many gastrointestinal problems in developing countries such as iran. we aimed to analyze the cost- effectiveness and cost- utility of the test-and-treat and empirical treatment strategies in managing helicobacter pylori infection.            methods: this was a markov based economic evaluation. effectiveness was defined as the symptoms free numbers and ...

conclusions the use of tdf in patients with hbeag-negative chb seemed to be a highly cost-effective strategy. compared with the other available medication options, tdf was the most cost-saving strategy. thus, tdf may be the best option as a first-line medication. patients can also be switched from other medications to tdf. results the results revealed that the tdf treatment strategy was more ef...

background: disease-modifying drugs (dmds) are a significant expenditure for treating multiple sclerosis (ms). however, there is limited report on assessment of the cost-utility of dmds compared with symptom management in the presence of long-term data. this study aimed to assess the lifetime cost-utility from the iranian healthcare perspectives of 4dmds relative to symptom management alone in ...